METHODS OF TREATING AGING AND METHODS OF SCREENING CANDIDATE AGENTS THEREFOR

摘要

A method of treating aging in a mammalian (e.g., human) subject comprises administering the subject a serotonin 2 (5-HT2) receptor antagonist in an amount effective to treat the aging (e.g., by prolonging or extending lifespan). Assays for identifying active compounds for such methods are also described, along with methods of treating subjects to receive chemotherapy or radiation to combat stress associated therewith.