PREPARATION METHODS OF AZOXYSTROBIN AND ITS ANALOGS
摘要
<p>Preparation methods of compounds of formula (I) comprise the following steps: (1) compounds of formula (II) react with formylation agents in aprotic solvent at the temperature between -20°C and 200°C in the presence of Lewis acid, then the organic base is added to promote the reaction to obtain intermediate products; (2) the above intermediate products react with methylation agents in the presence of alkali at the temperature between -20°C and 100°C to obtain compounds of formula (I).</p>