发明名称 SUBSTITUTED ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS
摘要 The present invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
申请公布号 US2009111830(A1) 申请公布日期 2009.04.30
申请号 US20060063018 申请日期 2006.02.15
申请人 ASTRAZENECA AB 发明人 WAGENEN BRADFORD VAN;UKKIRAMAPANDIAN RADHAKRISHNAN;CLAYTON JOSHUA;EGLE IAN;EMPFIELD JAMES R.;ISAAC METHVIN;MA FUPENG;SLASSI ABDELMALIK;STEELMAN GARY;URBANEK REBECCA;WALSH SALLY
分类号 A61K31/496;A61K31/4015;A61P25/00;C07D209/34;C07D401/14 主分类号 A61K31/496
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