<p>Provided herein are methods for introducing a polynucleotide into an extremophile, such as Pyrococcus fitriosis, by conjugation with a member of the family Enterobacteriaceae. Also provided are genetically engineered extremophiles, such as Pyrococcus furiosiis, that include an exogenous polynucleotide integrated into genomic DNA.</p>
申请公布号
WO2009055699(A1)
申请公布日期
2009.04.30
申请号
WO2008US81157
申请日期
2008.10.24
申请人
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;ADAMS, MICHAEL, W.W.;YANG, FEI;WESTPHELING, JANET