发明名称 METHOD FOR THE TREATMENT OF MAGNESIUM AND POTASSIUM DEFICIENCIES
摘要 A method for the treatment of depleted intracellular and serum magnesium levels by administration of a highly bioavailable magnesium salt is disclosed. A prescription dispensing system is also disclosed. The highly bioavailable magnesium salt can be administered alone or as adjunctive therapy in conjunction with various medications that cause or exacerbate depleted intracellular magnesium levels, such as renal magnesium wasting medications, including diuretics, immunosuppressants, chemotherapeutic agents, and antibiotics. The highly bioavailable magnesium salt can also be used as adjunctive therapy in conjunction with Class III anti-arrhythmic drugs to attenuate the QTc interval and reduce the risk of fatal arrhythmias, which are a common risk associated with Class III anti-arrhythmic drugs. The administration of a highly bioavailable magnesium salt in accordance with the present invention also serves to restore intracellular potassium levels to normal ranges in patients who remain hypokalemic despite potassium therapy.
申请公布号 WO2006121943(A3) 申请公布日期 2009.04.30
申请号 WO2006US17562 申请日期 2006.05.05
申请人 NICHE PHARMACEUTICALS, INC.;OFFEN, CHRISTOPHER;BRANDON, STEPHEN;HARRISON, CHARLES;WHITE, CHARLES;KLUGER, JEFFREY 发明人 OFFEN, CHRISTOPHER;BRANDON, STEPHEN;HARRISON, CHARLES;WHITE, CHARLES;KLUGER, JEFFREY
分类号 A61K31/33 主分类号 A61K31/33
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