COMPOSITIONS FOR CHEMICAL AND BIOLOGICAL DEFENSE, AND METHODS RELATED THERETO
摘要
<p>One aspect of the present invention relates to reactive compositions and methods of use thereof, wherein a metal oxide cluster is used to connect a reactive group (or groups) to the surface of a substrate. In certain embodiments, the reactive group in the compositions decomposes organophosphate agents through nucleophilic hydrolysis. In certain embodiments, the reactive group in the compositions is bactericidal. Remarkably, the use of metal oxide clusters in the disclosed compositions and methods permits incorporation of higher quantities of nucleophilic and bactericidal groups without the difficulties associated with having to pretreat the substrate prior to its association with the reactive groups.</p>
申请公布号
WO2009055128(A2)
申请公布日期
2009.04.30
申请号
WO2008US73460
申请日期
2008.08.18
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;HATTON, T., ALAN;BROMBERG, LEV, E.;ZHANG, HUAN