| 发明名称 |
AMINOPYRIDINE DERIVATIVES AS MODULATORS OF MGLUR5 |
| 摘要 |
<p>The present invention is directed to novel compounds (I) as modulators of metabotropic glutamate receptors (mG1uRs) 1. A compound of formula (I) wherein R1 is methyl. halogen or cyano; R2 h hydrogen or fluoro: R3 isC1-C3 tlfeyi or cyclopropyl; X is (Formula) to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds</p> |
| 申请公布号 |
WO2009054792(A1) |
申请公布日期 |
2009.04.30 |
| 申请号 |
WO2008SE51195 |
申请日期 |
2008.10.23 |
| 申请人 |
ASTRAZENECA AB;GRANBERG, KENNETH;HOLM, BJOERN |
发明人 |
GRANBERG, KENNETH;HOLM, BJOERN |
| 分类号 |
A61K31/4439;C07D413/14;A61P1/00;A61P1/04;A61P25/00;A61P25/22;C07D213/74;C07D401/14;C07D413/04 |
主分类号 |
A61K31/4439 |
| 代理机构 |
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