METHOD FOR FIXING COMPOUNDS COMPRISING PEPTIDE BONDS, SUCH AS PROTEINS, TO A MICROSYSTEM, AND MICROSYSTEM INCORPORATING THESE COMPOUNDS

摘要

The present invention relates to a method for fixing one or more compound(s) comprising peptide bonds, such as proteins, to a microsystem of the type comprising an array of electrodes covering a substrate, and to such a microsystem incorporating these compounds. The fixing method according to the invention relates to a microsystem (1) comprising an array of electrodes covering a substrate, and it comprises the following sequence of steps: a) electrolytically depositing a polymeric layer based on at least one hydrophobic electronically conductive polymer on at least one of these electrodes, via the electrode(s) being brought into contact with an electrolyte (7) comprising a monomer to be polymerized, and then b) bringing the hydrophobic polymeric layer thus obtained into contact with a peptide medium containing said compound(s) to be fixed, in order to immobilize the latter on said array essentially via hydrophobic bonds.