AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF

摘要

[PROBLEMS] To provide a therapeutic or prophylactic agent for frequent urination, urinary urgency or urinary incontinence associated with a lower urinary tract disease including overactive bladder, a lower urinary tract disease accompanied by a lower urinary tract pain such as interstitial cystitis and chronic prostatitis, or a disease accompanied by a pain, whose activity relies on its excellent trkA receptor-inhibiting activity. [MEANS FOR SOLVING PROBLEMS] Disclosed is a novel azolecarboxamide compound having a thiazole or oxazole ring bound to a benzene, pyridine, pyridazine, thiophene, pyrazole or pyrrole ring through a carboxamide or a salt of the azolecarboxamide compound. It is confirmed that the azolecarboxamide compound or the salt thereof has a potent trkA receptor-inhibiting activity. It is found that the azolecarboxamide compound or the salt thereof can be used as a highly effective and highly safe therapeutic or prophylactic agent for frequent urination, urinary urgency or urinary incontinence associated with a lower urinary tract disease including overactive bladder, a lower urinary tract disease accompanied by a lower urinary tract pain such as interstitial cystitis and chronic prostatitis, or a disease accompanied by a pain.