发明名称 HUMAN TOLL-LIKE RECEPTOR PROTEIN, RELATED REAGENT AND METHOD
摘要 <P>PROBLEM TO BE SOLVED: To provide promoting or reinforcing the beneficial activity of other lymphokines, and further a new receptor and relating compound for a ligand exhibiting a similarity to an interleukin 1-like composition and a method for using these substances. <P>SOLUTION: Nucleic acids encoding nine human receptors, designated DNAX Toll-like receptors 2-10 (DTLR2-10), homologous to the Drosophila Toll receptor and the human IL-1 receptor, purified DTLR proteins and fragments thereof, mono-/polyclonal antibodies against these receptors, and methods for diagnostic and therapeutic use. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009089713(A) 申请公布日期 2009.04.30
申请号 JP20080326610 申请日期 2008.12.22
申请人 SCHERING CORP 发明人 HARDIMAN GERARD T;ROCK FERNANDO L;BAZAN J FERNANDO;KASTELEIN ROBERT A
分类号 C12N15/09;C07K14/705;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02 主分类号 C12N15/09
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