METHODS AND SYSTEMS FOR SOLUTION BASED SEQUENCE ENRICHMENT AND ANALYSIS OF GENOMIC REGIONS

摘要

The present invention provides novel methods and systems for capturing and enrichment of target nucleic acids for reducing the complexity of target nucleic acids, preferably a genomic sample, for further analysis such as direct DNA sequencing, resequencing or SNP calling. In particular, the present invention provides for the enrichment of targeted sequences in a solution based format.