发明名称 |
ANTIGEN-SPECIFIC T-CELL PREPARATIONS FROM BONE MARROW |
摘要 |
<p>A method for the generation of antigen-specific T-cell preparations for adoptive therapy is provided, comprising the steps of obtaining lymphoid cells from the bone marrow of a patient in a first step, expanding the lymphoid cells in cell culture medium ex-vivo in the presence of at least one of IL2 and IL7 and or more antigens, yielding a T-cell preparation, and isolating the T-cell preparation from the culture medium in an isolation step. T-cell preparations provided according to the inventive method, and the use of such T-cell preparations for the treatment of infectious disease and cancer is also provided.</p> |
申请公布号 |
WO2009053109(A1) |
申请公布日期 |
2009.04.30 |
申请号 |
WO2008EP09186 |
申请日期 |
2008.10.24 |
申请人 |
LETSCH, ANNE;NA, IL-KANG;SCHEIBENBOGEN, CARMEN;VOLK, HANS-DIETER |
发明人 |
LETSCH, ANNE;NA, IL-KANG;SCHEIBENBOGEN, CARMEN;VOLK, HANS-DIETER |
分类号 |
A61K39/00;A61P35/00;C12N5/0783 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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地址 |
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