发明名称 |
FULLY HUMAN ANTI-VEGF ANTIBODIES AND METHODS OF USING |
摘要 |
<p>Disclosed herein are fully human antibodies and antigen-binding fragments thereof that specifically bind human VEGF and inhibit VEGF binding to VEGF-R1 and VEGF-R2, and therefore inhibit VEGF signaling. The antibodies and antigen-binding fragments disclosed herein may be used, for example, to treat angiogenesis and conditions associated with angiogenesis both in vivo and in vitro.</p> |
申请公布号 |
CA2702637(A1) |
申请公布日期 |
2009.04.30 |
申请号 |
CA20082702637 |
申请日期 |
2008.10.20 |
申请人 |
SCHERING CORPORATION;XOMA TECHNOLOGY LTD. |
发明人 |
RAMACHANDRA, SUMANT;MASAT, LINDA;HUANG, CHAO BAI;TAKEUCHI, TOSHIHIKO;KANTAK, SEEMA;BISHOP, WALTER ROBERT;HUANG, CHIN-YI |
分类号 |
C07K16/22;A61K39/395;C07K14/475;C12N15/13 |
主分类号 |
C07K16/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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