发明名称 |
CHOLESTEROL DERIVATIVES OF INHIBITORS OF VIRAL FUSION |
摘要 |
The present invention relates to compounds comprising at least ten contigous amino acids of the HR2 domain of a Type 1 viral fusogenic protein of an enveloped virus, or a derivative thereof, attached at the C-terminal to cholesterol or a derivative thereof; or a pharmaceutically acceptable salt thereof which inhibit viral fusion. Thus compounds of the invention are useful to prevent or treat diseases caused by an enveloped virus. |
申请公布号 |
WO2009053339(A2) |
申请公布日期 |
2009.04.30 |
申请号 |
WO2008EP64151 |
申请日期 |
2008.10.20 |
申请人 |
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.;PESSI, ANTONELLO;BIANCHI, ELISABETTA;INGALLINELLA, PAOLO |
发明人 |
PESSI, ANTONELLO;BIANCHI, ELISABETTA;INGALLINELLA, PAOLO |
分类号 |
A61K47/48;A61P31/18;C07K17/02 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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