The present application discloses an immunogenic composition comprising a Hib saccharide conjugate and at least two further bacterial saccharide conjugates wherein the Hib conjugate is present in a lower saccharide dose than the mean saccharide dose of all the at least two further bacterial saccharide conjugates.
申请公布号
ZA200710853(B)
申请公布日期
2009.04.29
申请号
ZA20070010853
申请日期
2007.12.13
申请人
GLAXOSMITHKLINE BIOLOGICALS S A.
发明人
BIEMANS, RALPH LEON;CAPIAU, CARINE;DUVIVIER, PIERRE;BOUTRIAU, DOMINIQUE;DENOEL, PHILIPPE;POOLMAN, JAN