Patch

摘要

The invention provides a patch device adapted for use in the transdermal administration to a patient of a composition including one or more pharmaceutically, cosmetically, pesticidally, prophylactically, and nutritionally active substance, the patch consisting of a layered construct adapted to be adhered to the skin of a patient and defining a cavity for receiving one or more disruptable containers of the composition or components of the composition to be administered between a proximal layer and a distal layer thereof, which proximal layer is adapted in use to be located in intimate contact with the skin of the patient and which distal layer is in use disposed on the outer side thereof, wherein the proximal layer is partially permeable to that composition, so that in use the integrity of the one or more containers may be disrupted thereby causing the composition to be disposed in the cavity and permeate from there through the proximal layer to be absorbed through the skin into the body of the patient. The invention further provides a method of applying an irritant to the skin of a user.