| 发明名称 |
Immunoglobin variants outside the Fc region |
| 摘要 |
The present invention relates to antibody variants outside the Fc region that alter binding affinity to one or more effector ligands, methods for their generation, and their therapeutic application. |
| 申请公布号 |
EP2053062(A1) |
申请公布日期 |
2009.04.29 |
| 申请号 |
EP20080020018 |
申请日期 |
2005.03.24 |
| 申请人 |
XENCOR, INC. |
发明人 |
LAZAR, GREGORY ALAN;KARKI, SHER BAHADUR |
| 分类号 |
C07K16/00;A61K39/395;C07K16/28;C07K16/30;C07K16/32;C07K16/44 |
主分类号 |
C07K16/00 |
| 代理机构 |
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