发明名称 |
Antibodies directed to CD20 and used thereof |
摘要 |
Antibodies directed to the antigen CD20 and uses of such antibodies are disclosed herein. In particular, fully human monoclonal antibodies directed to the antigen CD20. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3 are disclosed. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also disclosed. |
申请公布号 |
ZA200710496(B) |
申请公布日期 |
2009.04.29 |
申请号 |
ZA20070010496 |
申请日期 |
2006.05.25 |
申请人 |
ASTRAZENECA AB. |
发明人 |
GAZIT BORNSTEIN, GADI;GREEN, LARRY L;YANG, XIAODONG;QUEVA, CHRISTOPHE;BLAKEY, DAVID CHARLES;TABRIZI, MOHAMMAD |
分类号 |
A61P;C07K |
主分类号 |
A61P |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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