| 发明名称 |
Modulators of muscarinic receptors |
| 摘要 |
The present invention relates to spiro compounds of formula XX as modulators of muscarinic receptors, wherein R1, R2, R3, Z1, Z2, L, G, n, m, t and p are defined herein. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases. |
| 申请公布号 |
ZA200806028(B) |
申请公布日期 |
2009.04.29 |
| 申请号 |
ZA20080006028 |
申请日期 |
2008.07.10 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
MAKINGS, LEWIS R.;GARCIA-GUZMAN BLANCO, MIGUEL;HURLEY, DENNIS J.;DRUTU, IOANA;RAFFAI, GABRIEL;BERGERON, DANIELE M.;NAKATANI, AKIKO;TERMIN, ANDREAS P.;SILINA, ALINA |
| 分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
| 代理机构 |
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