发明名称 |
NANOPARTICLE COMPOSITIONS |
摘要 |
A method of Nanoparticle-based therapy for a mammalian subject is disclosed. The method uses Nanoparticles and/or Nanoparticles with outer surfaces that contain an affinity moiety effective to bind specifically to a biological surface at which the therapy is aimed, and a hydrophilic polymer coating. The hydrophilic polymer coating is made up of polymer chains either covalently linked or surface adsorbed to the polymer components. After a desired Nanoparticle biodistribution is achieved, the affinity agent binds to the target surface and helps internalize the Nanoparticles.
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申请公布号 |
KR20090041437(A) |
申请公布日期 |
2009.04.28 |
申请号 |
KR20097005377 |
申请日期 |
2009.03.16 |
申请人 |
NOVARTIS AG |
发明人 |
KUMAR SARAN;SHIEH WEN CHUNG;TOMER SEEMA;ZIELINSKI JOSEPH LAWRENCE |
分类号 |
A61K9/51;A61K31/675;A61K47/34;A61P3/14 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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