发明名称 |
METHOD FOR PREPARING AN OPTICALLY ACTIVE 1-[(4-CHLOROPHENYL)PHENYLMETHYL] -PIPERAZINE |
摘要 |
A method for preparing an 1-[(4-chlorophenyl)phenylmethyl]-piperazine with optical activity is provided to economically manufacture a compound by using camphoric acid and to be suitable for mass production. An R-1-[(4-chlorophenyl)phenylmethyl]-piperazine and S-1-[(4-chlorophenyl)phenylmethyl]-piperazine with optical activity is prepared by reacting 1-[(4-chlorophenyl)phenylmethyl]-piperazine with a chiral camphor acid. The chiral camphor acid is (1R,3S)-camphor acid or (1S,3R)-camphor acid.
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申请公布号 |
KR20090041194(A) |
申请公布日期 |
2009.04.28 |
申请号 |
KR20070106778 |
申请日期 |
2007.10.23 |
申请人 |
CHEMTECH RESEARCH INCORPORATION |
发明人 |
BYUN, IL SUK;KIM, YOUNG YOUN;LEE, WOO HWA;KIM, WAN JOO |
分类号 |
C07D295/073 |
主分类号 |
C07D295/073 |
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