发明名称 |
PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITION CONTAINING SAME |
摘要 |
A phenanthrene lactam derivative having the anticancer activity is provided to prevent and treat cancer and disease with excellent anticancer activity. A phenanthrene lactam derivative having chemical formula 1 is produced by reaction of the compound of chemical formula 2 and the compound of chemical formula 3 in a solution. R1, R2, R3, R4, R5, R6 and R7R is hydrogen, halogen, hydroxy, C1-6 alkyl, C1-6 alkoxy or aryloxy. R4 and R5, R5 and R6, or R6 and R7 forms dioxol. R8 is the hydrogen or the C1-6 alkyl. The composite for preventing caner and pharmaceutical treatment comprises the phenanthrene lactam derivative of chemical formula 1 or pharmaceutically allowable salt.
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申请公布号 |
KR20090039038(A) |
申请公布日期 |
2009.04.22 |
申请号 |
KR20070104435 |
申请日期 |
2007.10.17 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY |
发明人 |
HEO, JUNG NYOUNG;KIM, BUM TAE;MIN, YONG KI;CHOI, SANG UN;LEE, HYUK;CHANG, SUNG YOUN;PARK, NO KYUN;KIM, JOA KYUM;KIM, YOUNG HA;PARK, MI KYUNG |
分类号 |
C07D209/90;A61K31/403;A61P35/00 |
主分类号 |
C07D209/90 |
代理机构 |
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