发明名称 |
HYDROGELS FOR ORTHOPEDIC REPAIR |
摘要 |
Hydrogels intended for orthopedic applications, including repair and regeneration of cartilage, bone, joint surfaces and related tissues, must possess greater strength and toughness than hydrogels used in soft tissue repair. A hydrogel formulation is provided which has high strength, toughness, a suitable mechanical modulu s and low equilibrium hydration. It may also have controlled porosity or degradation time. It can be made to polymerize in sit u with high ("good" to "excellent") adherence to target tissue or surfaces. A preferred formulation for forming such gels comprises 40 to 80 % by weight of a low-molecular weight polar monomer and 30 to 10 % of a hydrophilic macromeric crosslinker.
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申请公布号 |
CA2384585(C) |
申请公布日期 |
2009.04.21 |
申请号 |
CA20002384585 |
申请日期 |
2000.09.08 |
申请人 |
FOCAL, INC. |
发明人 |
TRAVERSE, JOHN F.;AVILA, LUIS Z.;KRAMER, HILDEGARD M.;JARRETT, PETER K.;GOODRICH, STEPHEN D.;COURY, ARTHUR J. |
分类号 |
A61L27/00;C08J3/075;A61K31/785;A61L27/16;A61L27/34;A61L27/52;A61L31/06;A61L31/10;A61L31/14;C08F20/26;C08F290/04;C08F290/06 |
主分类号 |
A61L27/00 |
代理机构 |
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地址 |
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