发明名称 |
Inhibitors of kinases |
摘要 |
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
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申请公布号 |
US7521450(B2) |
申请公布日期 |
2009.04.21 |
申请号 |
US20070832976 |
申请日期 |
2007.08.02 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BHIDE RAJEEV S.;CAI ZHEN-WEI;QIAN LIGANG;BARBOSA STEPHANIE;LOMBARDO LOUIS;ROBL JEFFREY |
分类号 |
A61K31/53;C07D487/04;A61K31/5377;A61K31/541;A61K31/662;A61K45/00;A61K45/06;A61P1/04;A61P1/16;A61P3/04;A61P3/10;A61P7/06;A61P9/00;A61P9/06;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P13/08;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P17/02;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/16;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P31/10;A61P31/12;A61P31/18;A61P31/22;A61P35/00;A61P35/02;A61P35/04;A61P37/00;A61P37/02;A61P37/04;A61P37/06;A61P43/00;C07D487/02;C07F9/6561 |
主分类号 |
A61K31/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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