| 发明名称 |
Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (IGF-I) |
| 摘要 |
The invention provides compounds of formula in which R1, R2, R3 and R4 have the meanings defined in the specification; processes for the preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.
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| 申请公布号 |
US7521453(B2) |
申请公布日期 |
2009.04.21 |
| 申请号 |
US20040497744 |
申请日期 |
2004.11.08 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
BARLAAM BERNARD;PAPE ANDREW;THOMAS ANDREW |
| 分类号 |
C07D239/48;A61K31/505;A61K31/506;A61P35/00;A61P43/00;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D413/14 |
主分类号 |
C07D239/48 |
| 代理机构 |
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