BYSTANDER SUPPRESSION OF AUTOIMMUNE DISEASES

摘要

The invention is directed to a method for treating autoimmune diseases in mammals, the method comprising administering to the mammals an effective amount for treating the diseases of a bystander antigen, the antigen eliciting the release of transforming growth factor beta (TGF-.beta.) at a locus within the body of the mammals wherein T-cells contributing to autoimmune response are found to suppress the T-cells contributing to the disease. The invention is directed also to compositions comprising bystander antigens useful in the treatment of autoimmune diseases in mammals and to pharmaceutical formulations thereof.