发明名称 NON-ANTIGENIC TOXIN-CONJUGATE AND FUSION PROTEIN OF INTERNALIZING RECEPTOR SYSTEM
摘要 A conjugate of a toxin and a cytokine, and a fusion protein comprising a bispecific antibody that has a first specificity for a cell marker specific to a malignant cell and a second specificity for a region of IL-15.alpha., each optionally further comprising a radionuclide, are useful therapeutic reagents for treating leukemias and lymphomas.
申请公布号 CA2269060(C) 申请公布日期 2009.04.07
申请号 CA19972269060 申请日期 1997.10.14
申请人 IMMUNOMEDICS, INC. 发明人 GOLDENBERG, DAVID M.
分类号 C07K19/00;C12N15/09;A61K38/00;A61K38/17;A61K38/20;A61K38/46;A61K39/395;A61K47/48;A61K51/00;A61K51/08;A61P35/00;A61P35/02;C07K14/54;C07K14/715;C07K16/28;C07K16/30;C07K16/46;C12N9/22 主分类号 C07K19/00
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