发明名称 Process for the preparation of dihydroxy esters and derivatives thereof
摘要 <p>A process for the preparation of a compound of formula (I) which comprises either the stereoselective reduction of a compound of formula (II) to produce a compound of formula (III), and esterification of the a compound of formula (III) to produce a compound of formula (I), or esterification of a compound of formula (II) to produce a compound of formula (IV) and the stereoselective reduction of a compound of formula (IV) to produce a compound of formula (I), wherein X represents an optionally substituted hydrocarbyl linking group, R and R'' each independently represent an optionally substituted hydrocarbyl group, and R' represents an optionally substituted hydrocarbyl preferably an optionally substituted alkyl group. Described is a compound of formula (I) too.</p>
申请公布号 SK286746(B6) 申请公布日期 2009.04.06
申请号 SK20020001589 申请日期 2001.05.01
申请人 ASTRAZENECA UK LIMITED 发明人 HOLT ROBERT ANTONY;BLACKER ANDREW JOHN;REEVE CHRISTOPHER DAVID
分类号 C07C67/03;C07C69/675;C07D319/06;C12N9/20;C12P7/62;C12P17/06;C12R1/84 主分类号 C07C67/03
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