| 摘要 |
<p>The present invention relates to a compounds of general formula (I), wherein Y is (a) or (b), which are caspase inhibitors, in particular interleukin-1 beta converting enzyme (ICE) inhibitors, methods of preparing the same, pharmaceutical compositions containing the same and its use in the manufacture of a medicament for treating or preventing a disease selected from an IL-1 mediated disease, apoptosis, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, and degenerative diseases.</p> |
