| 摘要 |
A cancer sensitizer containing chlorogenic acid or derivative thereof is provided to show improved effects of cancer treatment and lower anti-cancer drug tolerance of cancer cells, thereby increasing sensitivity of the anti-cancer drug. A composition for inhibiting anti-cancer drug tolerance comprises chlorogenic acid or derivative thereof and a pharmaceutically allowable carrier. A composition for treating cancer contains the composition for inhibiting anti-cancer drug tolerance and anti-cancer drug. The anti-cancer drug is selected from the group consisting of mechloethamine, chlorambucil, phenylalanine, mustard, cyclophosphamide, ifosfamide, carmustine, lomustine, streptozotocin, busulfan, thiotepa, cisplatin, carboplatin, dactinomycin, doxorubicin, daunorubicin, idarubicin, mitoxantrone, plicamycin, mitomycin, C Bleomycin, vincristine, vinblastine, paclitaxel, docetaxel, etoposide, teniposide, topotecan and iridotecan.
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