摘要 |
The instant invention is based, at least in part, on the discovery that T-bet maintains host commensal relationships in the gastrointestinal tract. Accordingly, this invention provides methods of treating and/or preventing ulcerative colitis, and/or colon cancer, and/or preventing colonization of a subject's gastrointestinal tract with commensal bacteria that promote ulcerative colitis as well as methods of identifying agents that treat and prevent the same. |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;GLIMCHER, LAURIE, H.;GARRETT, WENDY, SARAH |
发明人 |
GLIMCHER, LAURIE, H.;GARRETT, WENDY, SARAH |