发明名称 |
ALKYLTHIO PYRIMIDINES AS CRTH2 ANTAGONISTS |
摘要 |
Provided herein are alkylthio substituted pyrimidine compounds having CRTH2 (G- protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity, useful for the treatment or prophylaxis of diseases associated with CRTH2 activity, including the treatment of allergic diseases, eosinophil-related diseases and basophil-related diseases.
|
申请公布号 |
CA2700524(A1) |
申请公布日期 |
2009.04.02 |
申请号 |
CA20082700524 |
申请日期 |
2008.09.24 |
申请人 |
ACTIMIS PHARMACEUTICALS, INC. |
发明人 |
LY, TAI WEI;RAAUM, ERIK D.;TRAN, MARIE CHANTAL S.-Y |
分类号 |
C07D239/38;A61K31/505;A61P29/00;C07D239/47;C07D239/58 |
主分类号 |
C07D239/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|