发明名称 |
ULTRAFINE L-CARNITINE, METHOD FOR PREPARING THE SAME, COMPOSITION CONTAINING THE SAME, AND METHOD OF USING THE SAME |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide L-carnitine having a configuration exhibiting a high bioavailability by oral administration, and its salt; to provide L-carnitine having a configuration easily preparable by combining another component (for example, an oil-based material) incapable of blending with L-carnitine of bulk, and its salt; and to provide L-carnitine having a configuration exhibiting a decreased hygroscopicity and its salt. <P>SOLUTION: L-carnitine provided has a particle size such that it substantially passes through a 100 USBS mesh sieve. The L-carnitine exhibits an increased bioavailability and a decreased hygroscopicity and may be conveniently formulated with oil-based materials to give a drug product. <P>COPYRIGHT: (C)2009,JPO&INPIT |
申请公布号 |
JP2009067809(A) |
申请公布日期 |
2009.04.02 |
申请号 |
JP20080284482 |
申请日期 |
2008.11.05 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA |
发明人 |
HASSEN KEN |
分类号 |
A61K31/205;A61K45/00;A23L1/305;A61K9/14;A61K31/05;A61K31/122;A61K31/194;A61K31/202;A61K31/221;A61K31/44;A61K47/04;A61P3/06;A61P9/00 |
主分类号 |
A61K31/205 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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