发明名称 ULTRAFINE L-CARNITINE, METHOD FOR PREPARING THE SAME, COMPOSITION CONTAINING THE SAME, AND METHOD OF USING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide L-carnitine having a configuration exhibiting a high bioavailability by oral administration, and its salt; to provide L-carnitine having a configuration easily preparable by combining another component (for example, an oil-based material) incapable of blending with L-carnitine of bulk, and its salt; and to provide L-carnitine having a configuration exhibiting a decreased hygroscopicity and its salt. <P>SOLUTION: L-carnitine provided has a particle size such that it substantially passes through a 100 USBS mesh sieve. The L-carnitine exhibits an increased bioavailability and a decreased hygroscopicity and may be conveniently formulated with oil-based materials to give a drug product. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009067809(A) 申请公布日期 2009.04.02
申请号 JP20080284482 申请日期 2008.11.05
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA 发明人 HASSEN KEN
分类号 A61K31/205;A61K45/00;A23L1/305;A61K9/14;A61K31/05;A61K31/122;A61K31/194;A61K31/202;A61K31/221;A61K31/44;A61K47/04;A61P3/06;A61P9/00 主分类号 A61K31/205
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