发明名称 METHODS FOR THE TREATMENT OF SCLERODERMA USING 1-OXO-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-METHYLISOINDOLINE
摘要 Methods of treating, preventing, correcting and/or managing skin diseases or disorders characterized by overgrowths of the epidermis, keratoses, scleroderma, cutaneous vasculitis, acne or wrinkles are disclosed. Specific embodiments encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent. Specific second active ingredients are capable of affecting or inhibiting cell growth or proliferation, removing or improving acne scars, or reducing or correcting wrinkle lines. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
申请公布号 US2009087407(A1) 申请公布日期 2009.04.02
申请号 US20080249350 申请日期 2008.10.10
申请人 CELGENE CORPORATION 发明人 ZELDIS JEROME B.;HARIRI ROBERT J.
分类号 A61K31/454;A61K31/19;A61K31/59;A61K36/28;A61K36/575;A61K38/21;A61K39/08;A61P17/00 主分类号 A61K31/454
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