PROXIMITY LIGATION ASSAY

摘要

The present invention relates to compositions and methods for sensitive, rapid and convenient assays to detect and/or quantify one or more target cell or tissue using ribonucleic acid as probes, wherein the method includes binding a first and a second ribonucleic acid probe, each of which binds specifically to the target cell or tissue, wherein the first and second probes each have a ribonucleic acid tail; ligating the first and second ribonucleic acids tails thereby producing a ligated ribonucleic acid template and performing amplification of the ribonucleic acid template across the first and second ribonucleic acids.