发明名称 REGULATION OF MATRIX METALLOPROTEINASE (MMP) GENE EXPRESSION IN TUMOR CELLS VIA THE APPLICATION OF ELECTRIC AND/OR ELECTROMAGNETIC FIELDS
摘要 <p>Methods and apparatus provide for treating and/or preventing tumor growth and/or spread, and/or other conditions in which Matrix Metalloproteinase (MMP) protein has been implicated in a patient, comprising generating at least one specific and selective electric signal that when applied to electrodes, one or more coils, or other field generating devices operatively disposed with respect to targeted tissue causes the generation of a specific and selective electric field in the targeted tissue that substantially down-regulates the gene expression of MMP protein in said targeted tissue as measured by mRNA production, and exposing said targeted tissue to the specific and selective electric field generated by said electrodes, one or more coils, or other field generating devices upon application of said at least one specific and selective electric signal thereto for a duration of between about 3-5 hours at predetermined intervals.</p>
申请公布号 WO2009042571(A1) 申请公布日期 2009.04.02
申请号 WO2008US77334 申请日期 2008.09.23
申请人 GENESTIM NASCENT ENTERPRISES LLC;BRIGHTON, CARL, T. 发明人 BRIGHTON, CARL, T.
分类号 A61N1/32 主分类号 A61N1/32
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