VACCINE FOR THE TREATMENT OF OSTEOARTHRITIS

摘要

The present invention pertains to a vaccine for the treatment of osteoarthritis in a vertebrate comprising IL-1 ß and optionally TNF-a cytokines or derivatives thereof, and in association with said IL-1 ß and optional TNF-a or derivatives thereof a part that is non-self with respect to the vertebrate such that the vaccine elicits an immune response in the vertebrate against IL-1 ß and TNF-a self-molecules of the said vertebrate.