发明名称 |
BIOMATERIAL |
摘要 |
A process for the preparation of a composite biomaterial comprising: providing a first substantially solid component comprising one or more of collagen, a glycosaminoglycan, albumin, hyaluronan, chitosan, and synthetic polypeptides comprising a portion of the polypeptide sequence of collagen, and optionally an inorganic material, said component having at least a surface portion that is porous; providing a fluid composition comprising one or more of collagen, a glycosaminoglycan, albumin, hyaluronan, chitosan, and synthetic polypeptides comprising a portion of the polypeptide sequence of collagen, and a liquid carrier, and optionally an inorganic material; contacting said fluid composition with said porous surface portion of said first component; cooling said fluid composition to a temperature at which the liquid carrier transforms into a plurality of solid crystals or particles; removing at least some of the plurality of solid crystals or particles by sublimation and/or evaporation. |
申请公布号 |
WO2008017858(A3) |
申请公布日期 |
2009.04.02 |
申请号 |
WO2007GB03046 |
申请日期 |
2007.08.10 |
申请人 |
CAMBRIDGE ENTERPRISE LIMITED;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;LYNN, ANDREW;BONFIELD, WILLIAM;WISSNER-GROSS, ZACHARY D.;HARLEY, BRENDAN A;YANNAS, IOANNIS V;GIBSON, LORNA J |
发明人 |
LYNN, ANDREW;BONFIELD, WILLIAM;WISSNER-GROSS, ZACHARY D.;HARLEY, BRENDAN A;YANNAS, IOANNIS V;GIBSON, LORNA J |
分类号 |
A61L27/56;A61L27/46;A61L27/48 |
主分类号 |
A61L27/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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