发明名称 |
Kappa-opioid receptor agonist comprising 2-phenylbenzothiazoline derivative |
摘要 |
The present invention provides º opioid receptor agonists comprising 2-phenylbenzothiazoline derivatives. The present invention relates to º opioid receptor agonists comprising compounds or salts thereof having the chemical structure represented by the general formula [I]. Namely, it is important for exhibition of the º opioid receptor agonist actions to have an alkyl group having an amino group at a phenyl group of 2-phenylbenzothiazoline as a substituent and to have an acyl group at a nitrogen atom of 2-phenylbenzothiazoline,
wherein R is alkyl having the amino group as the substituent; and R 1 is acyl.
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申请公布号 |
EP2042173(A2) |
申请公布日期 |
2009.04.01 |
申请号 |
EP20090000611 |
申请日期 |
2003.03.28 |
申请人 |
SANTEN PHARMACEUTICAL CO., LTD. |
发明人 |
TOKAI, MAKI;HONDA, TAKAHIRO;NIWA, MASASHI;OSUMI, YAEKO;FUJIMURA, K.;KOHNO, SHI-INCHI |
分类号 |
A61K31/428;A61P17/04;A61P19/02;A61P19/06;A61P25/04;A61P29/00;A61P43/00;C07D277/66;C07D417/12 |
主分类号 |
A61K31/428 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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