| 发明名称 |
METHODS OF PREPARING ZOFENOPRIL CALCIUM |
| 摘要 |
<p>The present invention relates to zofenopril calcium form A substantially free of other forms of zofenopril calcium and to zofenopril calcium having a chemical purity of more than 98.5%. The present invention also relates to methods of preparing such zofenopril calcium. It further relates to compositions comprising such zofenopril calcium. Zofenopril calcium, (4S)-1-[(2S)-3-benzoylthio-2-methylpropionyl]-4-(phenylthio)-L-proline calcium salt, has the following structure:</p> |
| 申请公布号 |
EP2041083(A1) |
申请公布日期 |
2009.04.01 |
| 申请号 |
EP20070733717 |
申请日期 |
2007.05.25 |
| 申请人 |
GENERICS (UK) LIMITED;MERCK DEV. CENTER PRIVATE LIMITED |
发明人 |
GORE, VINAYAK G.;PEHERE, ASHOK D.;GAIKWAD, AVINASH C.;VIJAYKAR, PRIYESH S. |
| 分类号 |
C07D207/16;A61K31/401;A61P9/00 |
主分类号 |
C07D207/16 |
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