摘要 |
The invention relates to 3-H-pyrazolopyridines according to the general formula (I):
in which A, B, D, E, R a , R 1 , R 2 , R 3 , R 4 , R 5 and q are as defined in the claims, and salts, N-oxides, solvates and prodrugs thereof, to pharmaceutical compositions comprising said 3-H-pyrazolopyridine compounds, to methods of preparing said 3-H-pyrazolopyridines, to intermediate compounds useful in said methods, to uses of said intermediate compounds in the preparation of said 3-H-pyrazolopyridines, as well as to uses of said 3-H-pyrazolopyridines for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
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申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
HARTUNG, INGO;KETTSCHAU, GEORG;SCHUMANN, INGRID;THIERAUCH, KARL-HEINZ;BOEMER, ULF |