Use of the enantiomer (1S,2R) of milnacipran for the preparation of a medicament

摘要

Disclosed is the use of a mixture of enantiomers of milnacipran (Z(±)-2-(aminomethyl)-N,N- diethyl-1-phenylcyclopropanecarboxamide) or pharmaceutically acceptable salts thereof, such mixture being substantially pure in the (1S,2R) enantiomer for the preparation of a drug intended for the treatment or the prevention of conditions or disorders in a patient that can be managed by double inhibition of serotonin (5-HT) and noradrenaline (NA) reuptake while limiting the risk of cardiovascular disturbances.