Method and probes for the detection of a tumor specific fusion protein

摘要

Disclosed is a set of at least a first and a second molecular probe, each probe provided with a dye wherein said dyes together allow energy transfer; at least one probe provided with a reactive group allowing juxtaposing said at least first and second probe wherein said reactive group allows to modulate juxtaposing said probes such that there is an increased likelihood of energy transfer between said dyes. A method is provided which permits detecting the presence of a fusion protein in a cell at the single cell level.