发明名称 Substituted Carboxylic Acids
摘要 The present invention relates to compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
申请公布号 US2009082392(A1) 申请公布日期 2009.03.26
申请号 US20080103082 申请日期 2008.04.15
申请人 THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC 发明人 VAN ZANDT MICHAEL C.;WHITEHOUSE DARREN;COMBS KERRY;HU SHAOJING
分类号 A61K31/343;A61K31/215;A61K31/404;A61K31/437;A61P3/10;C07C69/736;C07D209/08;C07D263/56;C07D263/57;C07D277/66;C07D307/80;C07D307/91;C07D307/92;C07D405/10;C07D417/04;C07D471/04 主分类号 A61K31/343
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