发明名称 |
Substituted Carboxylic Acids |
摘要 |
The present invention relates to compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
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申请公布号 |
US2009082392(A1) |
申请公布日期 |
2009.03.26 |
申请号 |
US20080103082 |
申请日期 |
2008.04.15 |
申请人 |
THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC |
发明人 |
VAN ZANDT MICHAEL C.;WHITEHOUSE DARREN;COMBS KERRY;HU SHAOJING |
分类号 |
A61K31/343;A61K31/215;A61K31/404;A61K31/437;A61P3/10;C07C69/736;C07D209/08;C07D263/56;C07D263/57;C07D277/66;C07D307/80;C07D307/91;C07D307/92;C07D405/10;C07D417/04;C07D471/04 |
主分类号 |
A61K31/343 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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