发明名称 INHIBITORS OF SERINE PROTEASES
摘要 The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.
申请公布号 WO2008106058(A3) 申请公布日期 2009.03.26
申请号 WO2008US02395 申请日期 2008.02.20
申请人 VERTEX PHARMACEUTICALS INCORPORATED;FARMER, LUC;BETHIEL, RANDY, SCOTT;JACOBS, DYLAN;PERNI, ROBERT, B.;MAXWELL, JOHN;COTTRELL, KEVIN;HALAS, SUMMER 发明人 FARMER, LUC;BETHIEL, RANDY, SCOTT;JACOBS, DYLAN;PERNI, ROBERT, B.;MAXWELL, JOHN;COTTRELL, KEVIN;HALAS, SUMMER
分类号 C07D487/10;A61K31/407;A61P31/12;C07D498/10 主分类号 C07D487/10
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