| 发明名称 |
FHBP- AND LPXL1-BASED VESICLE VACCINES FOR BROAD SPECTRUM PROTECTION AGAINST DISEASES CAUSED BY NEISSERIA MENINGITIDIS |
| 摘要 |
<p>The present invention generally provides methods and compositions for eliciting an immune response against Neisseria spp. bacteria in a subject, using vesicle vaccines made from Neisseria strains have decreased or no detectable expression of a product of LpxL1 gene, and which optionally overexpress fHbp.</p> |
| 申请公布号 |
WO2009038889(A1) |
申请公布日期 |
2009.03.26 |
| 申请号 |
WO2008US72028 |
申请日期 |
2008.08.01 |
| 申请人 |
CHILDREN'S HOSPITAL AND RESEARCH CENTER AT OAKLAND;GRANOFF, DAN;HOU, VICTOR |
发明人 |
GRANOFF, DAN;HOU, VICTOR |
| 分类号 |
C07K14/00 |
主分类号 |
C07K14/00 |
| 代理机构 |
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代理人 |
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