| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a new class 6-O-substituted erythromycin derivative having increased acid stability to erythromycin A and 6-O-methylerythromycin A, and enhanced activity to gram-negative bacteria and macrolide-resisting gram-positive bacteria. <P>SOLUTION: Provided are an antibacterial compound having structural formula (V) and the like as well as pharmaceutically permissible salts, esters or prodrugs thereof; pharmaceutical compositions comprising the compound; a therapeutic method of bacterial infection by administering the compound; and a production method of the compound. <P>COPYRIGHT: (C)2009,JPO&INPIT</p> |
