发明名称 |
Mitochondrial DNA variants associated with metabolic syndrome |
摘要 |
Provided are methods of identifying Metabolic Syndrome phenotypes for an organism or a biological sample derived therefrom which methods are based on detecting a polymorphism, haplotype, haplotype group, or haplotype subgroup in the mitochondrial genome of the organism and correlating the polymorphism or haplotype to a Metabolic Syndrome phenotype. Also provided are systems or kits for the detection of such polymorphisms or haplotypes and the correlation of the polymorphisms or haplotypes to a Metabolic Syndrome phenotype. Provided are methods of identifying a modulator of a Metabolic Syndrome phenotype and kits for the treatment of a Metabolic Syndrome phenotype.
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申请公布号 |
US2009082251(A1) |
申请公布日期 |
2009.03.26 |
申请号 |
US20080156958 |
申请日期 |
2008.06.04 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
WALLACE DOUGLAS C.;WANG PING H.;CHUANG LEE-MING |
分类号 |
A61K38/02;C12Q1/68;G01N33/50;G01N33/68 |
主分类号 |
A61K38/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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