摘要 |
<p>Pharmaceutical compositions that include a poorly water-soluble therapeutic compound, an aqueous solvent, an chelator/antioxidant, a buffer or buffer component, and a bulking agent. The pharmaceutical compositions can be orally ingested or administered parenterally. The pharmaceutical compositions can further be lyophilized to form a pharmaceutically acceptable cake that can be administered orally, e.g., as a solid oral dosage form; or reconstituted and administered parenterally, e.g. as a single i.v. bolus or iv infusion, or administered orally, e.g. as a drink solution.</p> |
申请人 |
NOVARTIS AG;BURANACHOKPAISAN, THITIWAN;JIANG, WENLEI;TONG, WEI-QIN;ZIELINSKI, JOSEPH, LAWRENCE;ZHU, JIAHAO;ZOBEL, HANS-PETER |
发明人 |
BURANACHOKPAISAN, THITIWAN;JIANG, WENLEI;TONG, WEI-QIN;ZIELINSKI, JOSEPH, LAWRENCE;ZHU, JIAHAO;ZOBEL, HANS-PETER |