发明名称 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING OPHTHALMIC DISORDERS
摘要 <p>The present invention relates to compositions and methods for the detecting, treating, and conducting research on ophthalmic disorders associated with photoreceptor cell death and/or retinal insult. In particular, the present invention provides compositions and methods for increasing IL-6 expression and/or activity (e.g., exogenous IL-6), activating IL-6 receptors (e.g., IL-6R, sIL6-R), activating pathway related compounds (e.g., STAT, FLIP), and/or activating related pathways (e.g., JAK/STAT pathway, TGF-ß pathway, Ahr pathway) in the diagnosis, treatment, and conducting research of ophthalmic disorders associated with photoreceptor cell death and/or retinal insult (e.g., retinal detachment).</p>
申请公布号 WO2009039388(A2) 申请公布日期 2009.03.26
申请号 WO2008US77038 申请日期 2008.09.19
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN;ZACKS, DAVID N. 发明人 ZACKS, DAVID N.
分类号 A61K31/16;A61K31/13;A61K39/39 主分类号 A61K31/16
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